Mechanism of the cellular transformation of newborn hamsters inoculated with herpes simplex type 2 virus
Kitsak, V.I.; Berdina, E.E.; Posevaia, T.A.; Chaplygina, N.M.; Orlova, N.G.
Voprosy Virusologii 28(4): 79-84
1983
ISSN/ISBN: 0507-4088 PMID: 6314675 Document Number: 212346
Combined virological, antigenic, electron microscopic, and molecular biologic study of the role of an oncovirus, herpes simplex type 2 virus (HSV-2), in the mechanisms of transformation of HSV-2-infected hamster cells was carried out. No expression of genetic information of the oncovirus could be detected. Cell transformation was shown to be associated with persistence and realization of HSV-2 genetic information in the transformed cells.
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