Damaging action of dithizone on insulin-releasing cells

Toroptsev, I.V.; Eshchenko, V.A.

Biulleten' Eksperimental'noi Biologii i Meditsiny 96(9): 23-25

1983


ISSN/ISBN: 0365-9615
PMID: 6351944
Document Number: 211397
Alterative action of dithizone was investigated in the experiments on various species of animals (fish, frogs, pigeons, mice, guinea pigs, golden hamsters, rats, rabbits, cats and dogs). The data received support the previously advanced suggestion that unsaturated (electrophilic) zinc complex formation is the basic mechanism of the alterative chelant's action.

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