HLA and skin disease in the Chinese

Chan, S.H.

Annals of the Academy of Medicine Singapore 12(1): 3-5

1983


ISSN/ISBN: 0304-4602
PMID: 6222684
Document Number: 210303
The HLA associations in skin diseases among the Chinese were reviewed. Tuberculoid leprosy was associated with B17 (RR = 4.1). This HLA association was reinforced in the finding of excess HLA haplotype sharing among affected siblings in multiple case families. In psoriasis the associations were with A1, AW30 and B13. The relative risk associated with AW30, B13 was 16.1. In SLE, mild patients were associated with B13 (RR = 3.7) and severe patients with B17.

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