Cytomegalo-immunoglobulin for intramuscular use. first experiences on bioavailability
Geursen, R.G.; Cieplik, P.; Geiger, H.; Gross-Albenhausen, E.; Ullrich, C.
Arzneimittel-Forschung 33(6): 898-899
1983
ISSN/ISBN: 0004-4172 PMID: 6311226 Document Number: 210010
Results are given on tolerability and bioavailability of an intramuscular immunoglobulin (Ig) preparation (BI 2.011) with high titer against cytomegalo-virus (CMV). For rapid and long-lasting protection a dosage of 0.2 ml/kg body weight anti-CMV-Ig with a titer of 1:50 000 (Enzyme-Linked Immunosorbent Assay) is recommended. Prophylaxis should be taken into account in seronegative patients suffering from immune defects, that experience transplantation surgery and/or multiple injections of blood products.