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Influence of anaesthesia on coagulation and fibrinolytic proteins

Richard, L.C.; Büller, H.R.; Bovilland, J.; ten Cate, J.W.

British Journal of Anaesthesia 55(9): 869-872

1983

ISSN/ISBN: 0007-0912
PMID: 6615674
Document Number: 208478
The changes in indices of coagulation (factors II, X and antithrombin III) and fibrinolytic factors (plasminogen and .alpha.2-antiplasmin) were studied in 30 patients during ophthalmic surgery. Patients (20) received thiopentone-N2O-enflurane anesthesia with either controlled (n = 10) or spontaneous (n = 10) ventilation. The remaining 10 patients received regional analgesia. No significant changes were observed in any of the measured indices in any group during or following surgery. Apparently, anesthesia has no direct influence on the coagulation or fibrinolytic proteins.

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