Characterization of the inflammatory infiltrate in lupus erythematosus lesions using monoclonal antibodies
Synkowski, D.R.; Provost, T.T.
Journal of Rheumatology 10(6): 920-924
1983
ISSN/ISBN: 0315-162X PMID: 6607342 Document Number: 208391
The inflammatory infiltrates of cutaneous lupus lesions from 14 patients with benign cutaneous, subacute cutaneous or systemic lupus erythematosus were examined for T and B lymphocytes, macrophages and Ia positive cells using monoclonal antibodies and a peroxidase antiperoxidase technique. T cells and Ia positive cells were present in abundance followed by B cells then macrophages. Approximately equal numbers of helper/inducer T cells (OKT4, Leu3a) and suppressor/cytotoxic T cells (OKT8, Leu-2a) were present in the inflammatory infiltrate.