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History of rotavirus research in children in Malawi: the pursuit of a killer

Cunliffe, N.; Wittel, D.; Ngwira, B.

Malawi Medical Journal the Journal of Medical Association of Malawi 21(3): 113-115

2009

ISSN/ISBN: 1995-7262
PMID: 20345020
DOI: 10.4314/mmj.v21i3.45631
Document Number: 208022
Rotavirus gastroenteritis is a major health problem among Malawian children. Studies spanning 20 years have described the importance, epidemiology and viral characteristics of rotavirus infections in the country. Despite a wide diversity of circulating rotavirus strains causing severe disease in young infants, a clinical trial of a human rotavirus vaccine clearly demonstrated the potential for rotavirus vaccination to greatly reduce the morbidity and mortality due to rotavirus diarrhoea in Malawi. This new enteric vaccine initiative represents a major opportunity to improve the health and survival of Malawian children.

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