Toxic shock syndrome caused by staphylococcal enterotoxin B. A report of 2 cases in children
Milner, L.S.; de Jager, J.; Thomson, P.D.; Doehring, R.O.
South African Medical Journal 63(21): 822-824
1983
ISSN/ISBN: 0256-9574 PMID: 6845109 Document Number: 207008
Two children with osteomyelitis, staphylococcal septicaemia and toxic shock syndrome (TSS) are reported. Both patients presented with fever, shock, scarlatiniform rash and diffuse mucositis. The multi-organ dysfunction which characterizes this syndrome was apparent in both patients, who had jaundice, functional renal impairment, diffuse myalgia and non-localizing neurological signs. One child developed toxic myocarditis and the other thrombocytopenia. Both showed a significant rise in antibody titre to enterotoxin B produced by the offending staphylococci, suggesting that this toxin was responsible for the TSS.