Pituitary function in 20 cases of prolactinoma in females
Eşanu, C.; Klepsch, I.; Calciu, G.; Bucur, D.; Popescu, L.G.
Endocrinologie 21(2): 131-139
1983
ISSN/ISBN: 0253-1801 PMID: 6408728 Document Number: 206585
Women with prolactinic pituitary tumor and FSH as compared to healthy women of the same age. Among the mechanisms implied in prolactin hypersecretion in females with prolactinic tumor are: low receptivity to dopamine, low dopamine production, elevated serotonin and TRH production, stress factors. Suppression of prolactin secretion with bromcriptine induces a rise in LHRH and consequently in LH and FSH. A drug treatment is suggested for prolactin hypersecretion in women with prolactinic pituitary tumor, consisting in association of small doses of bromcriptine, L-DOPA, metergoline and thyroxine, and avoidance of stress circumstances.