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Crescentic light-chain glomerulopathy. Report of a case

Lapenas, D.J.; Drewry, S.J.; Luke, R.L.; Leeber, D.A.

Archives of Pathology and Laboratory Medicine 107(6): 319-323

1983

ISSN/ISBN: 0003-9985
PMID: 6405721
Document Number: 205201
Light-chain glomerulopathy occurred in a middle-aged woman with adult-onset diabetes mellitus and IgG-kappa light-chain multiple myeloma. Unusual features of the glomerulopathy included the presence of numerous epithelial crescents and rapid progression to chronic renal failure. The aggressiveness of her disease may be related to her underlying diabetes mellitus and associated abnormalities in glomerular clearance of macromolecules, including immunoglobulin light chains.

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