Poisoning caused by the organophosphate parathion (E-605)
Windler, E.; Dreyer, M.; Runge, M.
Schweizerische Medizinische Wochenschrift 113(23): 861-862
1983
ISSN/ISBN: 0036-7672 PMID: 6879138 Document Number: 204931
In a 41-year-old patient administration of 5 g parathion led to respiratory failure and unconsciousness. Ventilatory support and antidote therapy were initiated early. However, only extensive gastric lavage and lowering of the plasma concentration by hemoperfusion with activated carbon resulted in the crucial elimination of the poison. Antidote and supportive measures may overcome the hazards of cholinesterase-inhibition, but not the direct toxic effect on the cardiovascular system which is currently regarded as the predominant cause of death.