Changes in the lysosomal apparatus of the human formed blood elements in the adaptation syndrome based on electron microscopy data
Koval', S.B.; Lunina, N.V.; Antipchuk, I.P.
Tsitologiia i Genetika 17(4): 61-66
1983
ISSN/ISBN: 0564-3783 PMID: 6623632 Document Number: 198526
An electron-microscopic examination of human leucocytes and thrombocytes under an effect of noninfectious stress factor (delivery) on organism shows that lysosomes of neutrophilic leucocytes move to plasmalemma, merge with it and secrete completely or partially their content to the blood plasma. Exocytosis of lysosomes results in a decrease of their amount in neutrophils. No changes in lysosomes of other leucocytes and thrombocytes are revealed. The fact that lysosomal neutrophilic enzymes enter the blood plasma is probably due to their participation in humoral regulation of organism functions.