The brain in cerebral malaria: a pathological study of 24 fatal cases in Papua New Guinea
SenGupta, S.K.; Naraqi, S.
Papua and New Guinea Medical Journal 35(4): 270-274
1992
ISSN/ISBN: 0031-1480 PMID: 1341088 Document Number: 198
The pathological features of cerebral malaria in 24 fatal cases are described. The cases included 18 adults aged 16 to 45 years and 6 children aged 1 to 15 years. All were unconscious before death. Gross pathological findings in the brain included cerebral oedema, vascular congestion and petechial haemorrhages. Histological examination revealed parasitized erythrocytes in the cerebral capillaries in all cases, ring haemorrhages in 6, hyaline material in the wall of medium-sized blood vessels in 4, and vascular thrombosis in 4 cases.
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