Efficacy and failure of phenobarbital in the prevention of febrile convulsions. Importance of familial antecedents
Palencia, R.; Cilleruelo, M.L.; Tresierra, F.; Blanco, A.
Anales Espanoles de Pediatria 18(2): 103-106
1983
ISSN/ISBN: 0302-4342 PMID: 6683949 Document Number: 197176
The authors analyze the value of phenobarbital for prophylaxis of new convulsions in a group of 370 patients who had previously had febrile seizures. Percentage of recurrences in phenobarbital treated cases (4 +/- 0,6 mg/Kg/d) was 18,67%, versus 55,89% in untreated children (p less than 0.001). The presence of family history of epileptic or febrile seizures is a risk factor (p less than 0.01) that facilitates failure of phenobarbital prophilaxis in future febrile seizures.