Prolonged suppression of experimental allergic encephalomyelitis in the Lewis rats: the effect of lipopolysaccharides

Raziuddin, S.; Morrison, D.C.

Journal of Immunology 128(3): 1486-1489

1982


ISSN/ISBN: 0022-1767
PMID: 6173441
Document Number: 196410
The current investigations have revealed that Lewis rats preimmunized with BP in CFA, and after recovery from the first episode of EAE, developed a second mild attack of EAE after challenge with BP/CFA at specified times. However, preimmunization of Lewis rats with BP complexed to LPS in CFA protects animals for a longer time from a second attack induced by BP/CFA challenge.

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