Adhesion induction by suture of varying tissue reactivity and caliber
Holtz, G.
International Journal of Fertility 27(3): 134-135
1982
ISSN/ISBN: 0020-725X PMID: 6128317 Document Number: 195204
Since postoperative peritoneal adhesion formation is a major cause for the generally poor results obtained in female infertility surgery, the importance of suture size and chronic reactivity in adhesion induction was evaluated in 2 experiments. In experiment 1, interrupted sutures (4/0 chromic, 4/0 polyglactin and 6/0 polyglactin) were placed in the dorsal surfaces of rabbit uterine horns. Adhesions were infrequently induced by all suture materials. In experiment 2, 4-cm-long incisions were made in the distal antimesenteric uterine horns. These were then reapproximated with running sutures (4/0 chromic, 4/0 polyglactin, 6/0 polyglactin and 8/0 nylon). Adhesion formation occurred to 16 of 18 incisions closed with 4/0 or 6/0 suture, whereas none of 5 incisions closed with 8/0 suture formed adhesions. Suture size rather than tissue reactivity may be paramount in adhesion induction.