Microcephaly vera, progressive motor neuron disease, and nigral degeneration
Halperin, J.J.; Williams, R.S.; Kolodny, E.H.
Neurology 32(3): 317-320
1982
ISSN/ISBN: 0028-3878 PMID: 7199649 Document Number: 195009
A patient is described who was microcephalic at birth. After attaining early motor milestones, she developed progressive lower motor neuron dysfunction of the limb and bulbar musculature, combined with dystonia and an action tremor. The pathology and possible pathogenesis are discussed.