Somatostatin in the medical treatment of fistula of the pancreas and the small intestine
Hild, P.; Stoyanov, M.; Dobroschke, J.; Aigner, K.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 58(38): 2195-2198
1982
ISSN/ISBN: 0037-1777 PMID: 6129704 Document Number: 193513
Somatostatin is a peptide hormone which inhibits the secretion of the growth hormone and certain gastrointestinal hormones. Its main effect is to reduce the gastric acid output and inhibit the exocrine function of the pancreas. It was therefore used as an adjuvant therapy in the conservative treatment of ten patients presenting with fistulas of the small intestine or pancreas. The treatment was successful in eight cases. The short halflife of the hormone makes continuous application of the somatostatin as important as the carrying on of the conservative treatment itself.