CSF immunoglobulins G in multiple sclerosis

Caputo, D.; Zaffaroni, M.; Procaccia, S.

Bollettino dell'Istituto Sieroterapico Milanese 61(5): 393-403

1982


ISSN/ISBN: 0021-2547
PMID: 6927183
Document Number: 192903
Three different methods were compared to detect an intrathecal IgG synthesis in cerebrospinal fluid of patients with Multiple Sclerosis. A preliminary investigation was carried out on serum and cerebrospinal fluid proteins fractionated by means of analytical isotachophoresis. This technique shows many advantages but isoelectrofocusing is still the most available technique in diagnostic trials.

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