Regression of liver cell adenoma. a follow-up study of three consecutive patients after discontinuation of oral contraceptive use
Bühler, H.; Pirovino, M.; Akobiantz, A.; Altorfer, J.; Weitzel, M.; Maranta, E.; Schmid, M.
Gastroenterology 82(4): 775-782
1982
ISSN/ISBN: 0016-5085 PMID: 6277724 Document Number: 190625
Three consecutive young female patients with unresected liver cell adenoma and a history of contraceptive use of several years' duration were followed up over a period of 2-4.5 yr after withdrawal of hormonal medication. One patient presented multiple adenomas and in another, the adenoma was associated with a Budd-Chiari syndrome due to bilateral thrombotic hepatic vein occlusion. Complete regression of the adenomas was documented in all 3 patients by ultrasonography, liver radionuclide scan, laparoscopy, or computerized tomography. It is concluded that, in selected cases, conservative management after withdrawal of hormonal contraception may be a valid alternative to surgical therapy.