Effect of sodium nitroprusside-induced hypotension on pulmonary deadspace
Khambatta, H.J.; Stone, J.G.; Matteo, R.S.
British Journal of Anaesthesia 54(11): 1197-1200
1982
ISSN/ISBN: 0007-0912 PMID: 7138723 Document Number: 189277
Deliberate hypotension with nitroprusside in man produced a 40% reduction in mean arterial pressure, but it did not cause any change in the pulmonary deadspace to tidal volume ratio (VD/VT). This was achieved by adequate hydration both before and during hypotension, as indicated by constant filling pressures. Apparently, deliberate hypotension does not increase VD/VT, and vasodilatation may bring about a relatively hypovolemic state and be responsible for the increase in VD/VT.
Document emailed within 1 workday
Related Documents
Wildsmith, J.A.; Drummond, G.B.; MacRae, W.R. 1975: Blood-gas changes during induced hypotension with sodium nitroprusside British Journal of Anaesthesia 47(8): 907-908Jackson, S.H.; Liebermann, M.C.; Smith, D.E. 1981: Sodium nitroprusside-induced hypotension as a supplemental therapeutic modality in postpartum hemorrhage Obstetrics and Gynecology 58(5): 649-651
Chang, C.L.; Yeh, F.C.; Ho, W.; Chen, H.I. 1985: Effects of sodium nitroprusside-induced hypotension on the cerebral and hindlimb blood flow in dogs Proceedings of the National Science Council Republic of China. Part B Life Sciences 9(3): 202-207
Rawlinson, W.A.; Loach, A.B.; Benedict, C.R. 1978: Changes in plasma concentration of adrenaline and noradrenaline in anaesthetized patients during sodium nitroprusside-induced hypotension British Journal of Anaesthesia 50(9): 937-943
Keaney, N.P.; McDowall, D.G.; Turner, J.M.; Lane, J.R.; Okuda, Y. 1973: The effects of profound hypotension induced with sodium nitroprusside on cerebral blood flow and metabolism in the baboon British Journal of Anaesthesia 45(6): 639
Hamaji, M.; Tashiro, C.; Oka, N.; Seki, T.; Kawashima, Y.; Yoshiya, I. 1983: Plasma catecholamine response to hypotension induced by trimethaphan and by sodium nitroprusside during nitrous oxide-oxygen-fentanyl anesthesia Medical Journal of Osaka University 34(1-2): 37-41
Borroni, V.; Pluchino, F.; Ferrario, L.; Lodrini, S.; Franceschetti, S.; Cefalà, A.; Avanzini, G. 1982: Controlled hypotension in the surgery of aneurysms in the circle of Willis. use of sodium nitroprusside and the value of EEG monitoring Minerva Anestesiologica 48(10): 613-618
Masuzawa, T. 1977: Deliberate deep hypotension with sodium nitroprusside during the radical surgery of 94 supratentorial aneurysms and arteriovenous malformations No Shinkei Geka. Neurological Surgery 5(9): 973-978
Ogawa, T.; Inoue, S.; Wauquier, A.; Hörig, C.; Cuesta, P. 1986: The renin-angiotensin, catecholamine system during controlled hypotension with sodium nitroprusside, trinitroglycerine and trimetaphan under balanced anesthesia Masui. Japanese Journal of Anesthesiology 35(10): 1482-1490
Wildsmith, J.A.; Sinclair, C.J.; Thorn, J.; MacRae, W.R.; Fagan, D.; Scott, D.B. 1983: Haemodynamic effects of induced hypotension with a nitroprusside-trimetaphan mixture British Journal of Anaesthesia 55(5): 381-389
Zäll, S.; Edén, E.; Winsö, I.; Volkmann, R.; Sollevi, A.; Ricksten, S.E. 1990: Controlled hypotension with adenosine or sodium nitroprusside during cerebral aneurysm surgery: effects on renal hemodynamics, excretory function, and renin release Anesthesia and Analgesia 71(6): 631-636
Lin, W.; Wei, X.; Kelimu, M.; Xue, H.; Lin, H.; Zhang, S.; Zhou, Z. 1999: Studies on DNA single strand breaks induced by sodium nitroprusside-nitric oxide donor Zhonghua Yu Fang Yi Xue Za Zhi 33(6): 360-362
Darbinian, T.M.; Kuliev, E.A.; Loginova, L.I.; Vladimirov, P.V. 1984: Warming of patients after hypothermic perfusion using sodium nitroprusside and pulmonary ventilation with a gas-anesthetic mixture heated to 46 degrees C Anesteziologiia i Reanimatologiia 2: 6-13
Maubec, E.; Matheron, R.; Tannières, M.L.; Benhaim, J.P.; Arbouet, C. 1988: Effect of labetalol on the hemodynamic response to sodium nitroprusside Cahiers d'Anesthesiologie 36(3): 193-198
Kumar, R.; Pathak, A.; Mathuriya, S.N.; Khandelwal, N. 2003: Intraventricular sodium nitroprusside therapy: a future promise for refractory subarachnoid hemorrhage-induced vasospasm Neurology India 51(2): 197-202
Dent, J.; Dodds, W.J.; Hogan, W.J.; Wood, J.D.; Arndorfer, R.C. 1979: Depressant effect of sodium nitroprusside on the lower esophageal sphincter of the opossum Gastroenterology 76(4): 784-789
Paul, V.; Reddy, L.; Ekambaram, P. 2005: A reversal by L-arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus Indian Journal of Physiology and Pharmacology 49(2): 179-186
Chohan, A.; Parmar, U.; Raina, S.K. 2012: Effect of sodium nitroprusside on morphological characters under chilling stress in chickpea (Cicer arietinum L.) Journal of Environmental Biology 33(4): 695-698
Auguet, M.; Delaflotte, S.; Chabrier, P.E.; Braquet, P. 1989: Vasoconstricting effect of endothelin. Interaction with atrial natriuretic factor, sodium nitroprusside, cicletanine and nifedipine Archives des Maladies du Coeur et des Vaisseaux 82(7): 1169-1172
Marks, G.S.; McLaughlin, B.E.; Jimmo, S.L.; Poklewska-Koziell, M.; Brien, J.F.; Nakatsu, K. 1995: Time-dependent increase in nitric oxide formation concurrent with vasodilation induced by sodium nitroprusside, 3-morpholinosydnonimine, and S-nitroso-N-acetylpenicillamine but not by glyceryl trinitrate Drug Metabolism and Disposition: the Biological Fate of Chemicals 23(11): 1248-1252