Changes in the electrical activity and coronary blood flow of a heterotopic heart allograft during a graft rejection crisis
Dvortsin, G.F.; Karpel', E.G.; Portnoĭ, V.F.
Kardiologiia 22(6): 54-58
1982
ISSN/ISBN: 0022-9040 PMID: 6750204 Document Number: 189019
In 12 experiments on dogs heterotopic cardiac allotransplantation on the recipient's neck has been performed. During the transplant survival its electrical activity and the coronary blood flow (CBF) were recorded with an implanted sensor of electromagnetic flowmeter. The combination of relatively low CBF and the amplitude of R wave during the first hours after transplantation with a high heart rate is a poor prognostic sign. Oscillations of CBF run parallel to changes of ECG when the viability of the transplant is retained, during the rejection crisis these changes do not correlate. The significance of comprehensive assessment of the cardiac function with the use of ECG and CBF measurement and comparison of their absolute figures and dynamics is shown to be of importance for the early diagnosis of the rejection crisis.