Dibekacin in bronchopulmonary infectious pathology
Gouin, F.; Basse, F.; Robert, D.; Auboyer, C.
La Nouvelle Presse Medicale 11(46): 3447-3450
1982
ISSN/ISBN: 0301-1518 PMID: 7155856 Document Number: 188538
Thirty six patients in an intensive care unit with a bacterial bronchopulmonary infection were treated with intraparenteral dibekacin at a dose of 3 mg/kg/day. Mean age of the patients was 55 years and the mean duration of treatment 14 days. Biological material was obtained by fibro-aspiration or pleural tap. One or more organisms were identified in 36 cases. These were essentially staphylococci and Gram negative bacilli sensitive to dibekacin. Results showed a favourable course in 26 cases and a clinical improvement in 10. Clinical and biological tolerance was good. No clinical manifestations of cochleo-vestibular toxicity were seen.