Double immunofluorescence detection of HBsAg and HBcAg in Councilman bodies of the liver

Storch, W.

Leber Magen Darm 12(4): 146-149

1982


ISSN/ISBN: 0300-8622
PMID: 6290808
Document Number: 187920
It could be shown by double immune fluorescence methods that HBsAg and/or HBcAg were present in Councilman bodies of the liver as well as in normal hepatocytes in biopsy specimens of a patient with HBsAg-seronegative chronic active hepatitis. These findings support earlier observations, that HBsAg is deposited in necrotic liver cells, and it supports the hypothesis, that Councilman bodies are formed under the influence of virus.

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