Acquired postganglionic cholinergic dysautonomia: case report and review of the literature

Inamdar, S.; Easton, L.B.; Lester, G.

Pediatrics 70(6): 976-978

1982


ISSN/ISBN: 0031-4005
PMID: 6128711
Document Number: 187029
An 8-year-old girl with acute abdominal pain had cholinergic autonomic dysfunction. There have been only four patients with acquired postganglionic cholinergic dysautonomia described in the literature. The characteristic clinical features are atony of the bowel and bladder, lack of tears, saliva, and sweat, internal ophthalmoplegia, and normal adrenergic functions. Special studies for autonomic nervous function help in confirming this diagnosis. The exact pathogenesis of the disorder is still not clear. This case demonstrates successful treatment with bethanechol chloride.

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