Properties of acetylcholine receptors translated by cat muscle mRNA in Xenopus oocytes

Miledi, R.; Parker, I.; Sumikawa, K.

EMBO Journal 1(11): 1307-1312

1982


ISSN/ISBN: 0261-4189
PMID: 6144542
Document Number: 186506
Poly(A)+ mRNA, extracted from denervated skeletal muscles of the cat, directs the synthesis of acetylcholine receptors in Xenopus laevis oocytes. The receptors are inserted in the oocyte membrane where they form acetylcholine receptor-channel complexes which have properties like those of the native receptors in the muscle membrane.

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