Immunologic selection of donors and recipients in renal graft: transplantation antigens
Seignalet, J.; Mourad, G.; Mion, C.
Nephrologie 3(2): 73-79
1982
ISSN/ISBN: 0250-4960 PMID: 6750427 Document Number: 186316
For the immunologic selection of donors and recipients in renal transplantation, several antigens must be considered: ABO and Lewis antigens identified by red cell typing, HLA-A, HLA-B and HLA-DR antigens identified by leucocyte typing and HLA-D antigens explored by mixed lymphocyte reaction (MLR). In renal grafts with living related donor, the best donor is ABO compatible, HLA-A and B identical, MLR negative with the recipient. In renal grafts with cadaver donor, the best recipient is ABO and Lewis compatible and must present the greatest number of HLA-A, B and DR identities with the donor. The number of cadaver donors is relatively small and the selected recipient does not however present a good HLA compatibility with his donor.