Estrogen receptors and response to chemotherapy in advanced breast cancer
Cocconi, G.; De Lisi, V.; Mori, P.; Bozzetti, C.
Tumori 68(1): 67-71
1982
ISSN/ISBN: 0300-8916 PMID: 7071948 Document Number: 182854
The relationship between receptor status and response to combination chemotherapy was retrospectively analyzed in 50 patients with advanced breast carcinoma, previously untreated with systemic therapy. Overall objective response rate to combination chemotherapy was similar in ER+ cases (14 of 33, 42%) and in ER- (9 of 17, 53%). The median duration of response was significantly longer in ER+ cases (48 wk) than in ER- ones (26 wk, P = 0.03). Response rate to cytotoxic chemotherapy does not appear to correlate with ER status.
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