Pancreatic Injury in COVID-19 Patients

Bansal, P.; Margekar, S.L.; Suman, V.; Sud, R.; Meena, S.; Sharma, A.K.; Islam, S.Y.; Gurtoo, A.; Agrawal, A.; Pangtey, G.S.; Prakash, A.

Journal of the Association of Physicians of India 68(12): 58-60


ISSN/ISBN: 0004-5772
PMID: 33247644
Document Number: 18225
Coronavirus disease 2019 (COVID 2019) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may cause multisystem dysfunction. We studied pancreatic injury (serum amylase and serum lipase levels) in COVID-19 patients. A retrospective study involving 42 COVID-19 patients (diagnosed by real-time PCR) admitted to a tertiary care hospital was conducted. Serum amylase and serum lipase levels were analysed in relation to severity of COVID-19 and mortality. Mean age of patients was 50 ± 16 years, with male to female ratio of 3.7:1. Serum amylase was elevated in 14 patients (33%). Serum lipase was elevated in 7 out of 29 patients (24.1%). Mortality was seen in 18 patients (42.8%). Serum amylase or lipase did not correlate with severity of COVID-19 or its mortality. However, both patients who had high lipase (>3times) died. The prevalence of hyperamylasemia in patients of COVID-19 was 33%, while that of elevated lipase was 24.1%. Pancreatic injury failed to show any statistically significant relation to severity or outcome of COVID-19.

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Pancreatic Injury in COVID-19 Patients