Top Abstract Purchase Related
Home
>
Node
>
Subnode

Double-blind multicenter comparison of 1,200 mg. and 1,000 mg. cimetidine in hospitalized and ambulatory duodenal ulcer patients

Graham, D.Y.; Schwartz, J.T.; Sabesin, S.M.; Mann, J.A.; Davis, W.D.; Font, R.G.; Cohen, N.N.

American Journal of Gastroenterology 76(6): 500-505

1981

ISSN/ISBN: 0002-9270
PMID: 7036712
Document Number: 182153
A multicenter double-blind study was made to compare whether 1,000 mg dosage of cimetidine, the dose commonly employed in the United Kingdom, was as effective as the 1,200 mg. dose recommended in the United States for the treatment of duodenal ulcer. Our second goal was to test whether hospitalization would enhance the efficacy of cimetidine in the healing of duodenal ulcer. There was no difference in healing rate after either one (40%) or four (86%) weeks of therapy. In addition, hospitalization (one week) did not enhance the efficacy of cimetidine therapy.

Document emailed within 1 workday
Secure & encrypted payments

Gough, K.R.; Bardhan, K.D.; Crowe, J.P.; Korman, M.G.; Lee, F.I.; Reed, P.I.; Smith, R.N. 1985: Ranitidine and cimetidine in the prevention of recurrence of duodenal ulcer. A randomized, double-blind, multicenter comparative study Fortschritte der Medizin 103(37): 878-882
Baccaro, J.C.; González del Solar, C.; Laudanno, O.; Mauro, E.; Mazure, P.A.; Pardo, R.; Pulpeiro, A.; Rubio, H.; Tomatis, H. 1987: Misoprostol and cimetidine in the treatment of active duodenal ulcer. Multicenter, double-blind, clinico-endoscopic study. the Argentine experience Acta Gastroenterologica Latinoamericana 17(3): 235-240
Cambielli, M.; Evangelista, A.; Guslandi, M.; Bierti, L.; Benvenuti, C.; Tittobello, A. 1979: Double blind comparison between cimetidine and gefarnate in cases of duodenal ulcer Acta Hepato-Gastroenterologica 26(4): 326-330
Petite, J.P.; Slama, J.L.; Licht, H.; Lemerez, M.; Coste, T.; Andrieu, J.; Grimaud, J.C.; Julien, H.; Dupuis, J.; Sallerin, V. 1993: Comparison of lansoprazole (30 mg) and omeprazole (20 mg) in the treatment of duodenal ulcer. a multicenter double-blind comparative trial Gastroenterologie Clinique et Biologique 17(5): 334-340
Dyck, W.P.; Belsito, A.; Fleshler, B.; Liebermann, T.R.; Dickinson, P.B.; Wood, J.M. 1978: Cimetidine and placebo in the treatment of benign gastric ulcer: a multicenter double blind study Gastroenterology 74(2 Part 2): 410-415
Takemoto, T.; Kimura, K.; Okita, K.; Tsuneoka, K.; Ohshiba, S.; Namiki, M.; Fukuchi, S.; Miyake, T.; Fukutomi, H.; Okazaki, Y. 1987: Efficacy of sucralfate in the prevention of recurrence of peptic ulcer--double blind multicenter study with cimetidine Scandinavian Journal of Gastroenterology. Supplement 140: 49-60
Shrivastava, R.K.; Shah, B.K.; Siegal, H. 1985: Doxepin and cimetidine in the treatment of duodenal ulcer: a double-blind comparative study Clinical Therapeutics 7(2): 181-189
Patty, I.; Tárnok, F.; Deák, G.; Mózsik, G. 1988: Cimetidine and placebo-cimetidine in the treatment of patients with chronic gastric ulcer (a multiclinical randomized double-blind comparative study) Acta Medica Hungarica 45(1): 83-95
Vantrappen, G.; Janssens, J.; Popiela, T.; Kulig, J.; Tytgat, G.N.; Huibregtse, K.; Lambert, R.; Pauchard, J.P.; Robert, A. 1982: Effect of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer: a double-blind multicenter study Gastroenterology 83(2): 357-363
Arber, N.; Avni, Y.; Eliakim, R.; Swissa, A.; Melzer, E.; Rachmilewitz, D.; Konikoff, F. 1994: A multicenter, double-blind, randomized controlled study of omeprazole versus ranitidine in the treatment of duodenal ulcer in Israel Israel Journal of Medical Sciences 30(10): 757-761
Zaterka, S.; Massuda, H.; Chinzon, D.; Eisig, J.N.; Miszputen, S.; Kendo, M.; Silva, A.E.; Ferrari Júnior, A.P.; Castro, L.P.; Castro, F.J. 1993: Treatment of duodenal ulcer with omeprazole or ranitidine in a Brazilian population: a multicenter double-blind, parallel group study American Journal of Gastroenterology 88(3): 397-401
Parente, F.; Bianchi Porro, G.; Canali, A.; Bensi, G. 1995: Double-blind randomized, multicenter study comparing aluminium phosphate gel with rantitidine in the short-term treatment of duodenal ulcer Hepato-Gastroenterology 42(2): 95-99
Amouretti, M.; Ansenay, M.; Bader, J.P.; Baillet, J.; Bel, A.; Belaïche, J.; Benzenou, A.; Bertrand, G.; Bonfils, S.; Boucekkine, T. 1985: Efficacy of ranitidine and cimetidine in the treatment of gastric or duodenal ulcer resistant to an initial treatment with cimetidine. Multicenter controlled therapeutic trial Gastroenterologie Clinique et Biologique 9(2): 147-152
Bader, A.P.; Morin, T.; Druguet, M.; Lambert, R.; Dupuy, P.; Bétourné, C. 1980: Prevention by cimetidine of duodenal ulcer relapses: a multicenter controlled trial Gastroenterologie Clinique et Biologique 4(3): 188-193
Hu, F.L.; Jia, B.Q.; Chen, B.W. 1987: Ranitidine and cimetidine in short-term treatment of duodenal ulcer and their acid inhibitory effect in patients with duodenal ulcer Zhonghua Nei Ke Za Zhi 26(8): 468-470; 510
De Jesús Villalobos, J.; Vargas, F.; Arroyo de Anda, R.; Barrera, A.; Centeno, F.; Angel Córdova, J.; Marín, E.; Moreno, J.; Peña, F.; Saénz, V. 1988: Famotidine versus cimetidine in the treatment of non-complicated duodenal ulcer. a multicenter study Revista de Gastroenterologia de Mexico 53(1): 7-13
Holtermüller, K.H.; Liszkay, M.; Bernard, I.; Haase, W. 1992: Therapy of stomach ulcer--a comparison between the low dosage antacid hydrotalcite and ranitidine--results of a randomized multicenter double-blind study. Talcivent Study Group Zeitschrift für Gastroenterologie 30(10): 717-721
Moser, U.; Waldburger, M.; Schwarz, H.A.; Gobelet, C.A. 1989: Double-blind randomized multicenter study with tenoxicam, piroxicam and diclofenac sodium retard in the treatment of ambulatory patients with arthroses and soft tissue rheumatism Schweizerische Rundschau für Medizin Praxis 78(10): 263-269
Moshal, M.G.; Spitaels, J.M.; Khan, F. 1981: Tri-potassium di citrato bismuthate chewing tablets and cimetidine tablets in the treatment of duodenal ulcers. a double-blind double-dummy comparative study South African Medical Journal 60(11): 420-423
Machado, L.P.; Borjas, J.A.; Guelrud, M.; Beker, S. 1979: Randomized double-blind evaluation of the treatment of gastric ulcer with cimetidine vs placebo G.E.N 32(4): 461-466