Alpha-1-antitrypsin and cystic fibrosis
Pecau, Y.; Feigelson, J.; Feingold, J.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 57(29-32): 1306-1309
1981
ISSN/ISBN: 0037-1777 PMID: 6269206 Document Number: 181488
A methodical study of the alpha-1-antitrypsin serum level and the Pi type in 69 CF children, 156 CF heterozygote parents and 200 blood donors from Paris, has been made. Although the PiZ allele frequency was found to be higher in the CF population, especially in fathers, than in the reference population, the difference is not statistically relevant. Therefore there does not seem to be a relation between cystic fibrosis and the Pi alleles system.