Amiodarone pigmentation. a rare, but typical drug side-effect
Korting, H.C.; Kolz, R.; Schmoeckel, C.; Balda, B.R.
Der Hautarzt; Zeitschrift für Dermatologie Venerologie und verwandte Gebiete 32(6): 301-305
1981
ISSN/ISBN: 0017-8470 PMID: 7263236 Document Number: 180667
Amiodarone is one of the most effective antiarrhythmic and anti-anginose drugs. A rare but typical side-effect with an incidence of 1:100 is sunburn, and of 1:1,000 a black-violet to slaty pigmentation of the sun-exposed skin areas. According to histochemical and ultrastructural findings the skin pigment deposits are considered to be lipofuscin.