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Vascular stability and middle molecules removal in hypertonic haemodiafiltration

Cambi, V.; Buzio, C.; Arisi, L.; Calderini, C.; David, S.; Manari, A.; Bono, F.; Zanelli, P.

Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 18: 681-689

1981

ISSN/ISBN: 0071-2736
PMID: 7329996
Document Number: 179857
Hypertonic haemodiafiltration is a simultaneous hypertonic (delta 550, Na 275mEq/L) low volume (7.2 litres) haemofiltration and hypotonic (delta 282) short time (180') haemodialysis. Reduction of the predialysis body pool of MM (-48 per cent) and small molecules (-33 per cent) was obtained. No relationship between vascular stability and MM removal was observed. However, a net UF of 20.5ml/min and a greater removal of solutes up to 1500 daltons mw were obtained with a three hours thrice weekly dialysis programme.

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