Effect of carbon dioxide and pH on susceptibility of Bacteroides fragilis group to erythromycin

Hansen, S.L.; Swomley, P.; Drusano, G.

Antimicrobial Agents and Chemotherapy 19(2): 335-336

1981


ISSN/ISBN: 0066-4804
PMID: 6812492
Document Number: 178519
The effects of pH and incubation in a CO2-containing atmosphere were examined on the activity of erythromycin against 81 strains of the B. fragilis group. A striking reduction in erythromycin activity was noted when the pH decreased below 7.0 and when the organisms were incubated with CO2.

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