Sulindac (Clinoril) hepatitis
Dhand, A.K.; LaBrecque, D.R.; Metzger, J.
Gastroenterology 80(3): 585-586
1981
ISSN/ISBN: 0016-5085 PMID: 7450449 Document Number: 177917
A patient with sulindac-induced hepatitis is presented. Sulindac, an antiinflammatory agent, was confirmed as the cause of the patient's liver disease when hepatic dysfunction abruptly recurred after an inadvertent reexposure to sulindac and quickly resolved when the drug was withdrawn. The prompt reappearance of fever, chills, pruritus, rash, tender hepatomegaly and abnormal liver tests after only 2 doses of sulindac suggested a hypersensitivity reaction.