A case of sulindac-induced enteropathy resulting in jejunal perforation
Yoon, K.H.; Ng, S.C.
Annals of the Academy of Medicine Singapore 27(1): 116-119
1998
ISSN/ISBN: 0304-4602 PMID: 9588286 Document Number: 491129
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed for rheumatic conditions. Their effects on the upper gastrointestinal tract are well recognised. Clinically important damage to the small intestines is less common and often unrecognised. We report a case of sulindac-induced jejunal perforation in a rheumatoid arthritis (RA) patient with previous gastrectomy for gastric carcinoma. The prevalence, diagnosis, pathogenesis and treatment options of NSAID-induced enteropathy will be discussed.