On the calculation and the evaluation of combinations of active substances
Groeger, U.; Lang, S.; Michel, H.J.
Die Pharmazie 36(2): 81-87
1981
ISSN/ISBN: 0031-7144 PMID: 7232493 Document Number: 177798
A survey is given of publications on the calculation of the combined effects of bioactive substances and on the statistical analysis of the results from combination studies. The dose-response relationships for the two essential types of combination, the independent and the equivalent mode of action, are stated and explained by typical classes of dose-response equations.