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On the pharmacokinetics of tiaprofenic acid and its possible interactions with acetylsalicylic acid and aluminum hydroxide

Marećek, N.; Lücker, P.W.; Penth, B.; Altmayer, P.; Wetzelsberger, K.

Arzneimittel-Forschung 31(1): 116-120

1981

ISSN/ISBN: 0004-4172
PMID: 6971108
Document Number: 176742
To clarify the question whether pharmacokinetic properties of tiaprofenic acid (presumable trade name Surgam) can be changed by simultaneous application of aluminum hydroxide or acetylsalicylic acid (ASA) a randomized study of 7 healthy volunteers was carried out. The results show that the bioavailability as well as the pharmacokinetic profile of orally administered tiaprofenic acid is not changed by the mentioned compounds.

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