Parenthood diagnosis within a family. II. Determination of an optimal sequence of genetic markers

Chastang, C.; Gremy, F.

Annales de Genetique 24(1): 21-24

1981


ISSN/ISBN: 0003-3995
PMID: 6971611
Document Number: 175854
The rapid discovery of new markers systems makes it impossible for financial reasons to study the polymorphism determination of all known genetic markers when dealing with parenthood problems. The percentage of rejected subjects with respect to the (mother, children) set should be used as a decision tool to define a sequence which provides the maximum information for the minimum cost. This decision rule is evaluated with 150 families whose polymorphism is determined on the same sequence of 20 genetic markers.

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