Lipid antioxidant properties of naloxone in vitro
Koŕeh, K.; Seligman, M.L.; Flamm, E.S.; Demopoulos, H.B.
Biochemical and Biophysical Research Communications 102(4): 1317-1322
1981
ISSN/ISBN: 0006-291X PMID: 7317053 Document Number: 175274
Evidently naloxone diminishes iron-initiated and catalyzed peroxidation in liposomes in a concentration-dependent manner. This supports the hypothesis that the action of naloxone in vivo during amelioration of spinal cord trauma and hemorrhagic shock may substantially involve its lipid antioxidant properties.
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