Hormonal transformation characteristics of endometrial adenoacanthoma in the process of progestin treatment
Shenderëva, T.S.; Shvedova, L.A.
Voprosy Onkologii 27(10): 52-56
1981
ISSN/ISBN: 0507-3758 PMID: 7303557 Document Number: 174951
Changes in the histological structure of endometrial adenoacanthoma, as a result of treatment with 17 alpha-hydroxyprogesterone capronate, are discussed. The biopsy and resected material obtained from 11 patients was studied. It was shown that hormono-therapy results in an increased structural and functional differentiation of the glandular and squamous-cell components of tumor. Sensitivity to 17 alpha-hydroxyprogesterone capronate was established in 81.1% +/- 11.6 of patients.