New pharmaceuticals in systemic mycoses
Plempel, M.
Zeitschrift für Hautkrankheiten 56(17): 1109-1125
1981
ISSN/ISBN: 0301-0481 PMID: 7293300 Document Number: 173905
The chemotherapy of systemic fungal infections remains problematic due to a lack of alternative agents. There are only 3 drugs available: Amphotericin B, 5-Fluorcytosine and the new iv.-formulation of Miconazole. There are as yet limited experiences concerning one of the Imidazole-derivatives of the new generation, Ketoconazole. The main antimycotic and pharmacokinetic properties of these drugs will be discussed.