Effects of angiotensin on the human lower esophageal sphincter pressure

Stanciu, C.; Frasin, M.; Cijevschi, C.; Bălan, G.; Pancu, D.; Hăulică, I.; Stanciu, C; Frasin, M; Cijevschi, C; Balan, G; Pancu, D; Haulica, I

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Effects of angiotensin on the human lower esophageal sphincter pressure

Stanciu, C.; Frasin, M.; Cijevschi, C.; Bălan, G.; Pancu, D.; Hăulică, I.

Medecine Interne 19(4): 359-361

1981

ISSN/ISBN: 0377-1202

PMID: 7336096

Document Number: 173867

I.v. infusions of angiotensin II (A II) in doses of 1.0, 2.0, 3.0, 4.0 and 5.0 ng/kg per min induced graded increases of the lower esophageal sphincter pressure (LESP) in healthy subjects. The effect of A II on LESP was not antagonized by i.v. administration of an atropine bolus. A II may act directly on the specific receptor in the LES and indirectly via the adrenergic nervous system.