A new method for studying the deformability of isolated erythrocyte membranes
Heath, B.P.; Wyatt, J.L.; Mohandas, N.; Shohet, S.B.
Progress in Clinical and Biological Research 56: 195-203
1981
ISSN/ISBN: 0361-7742 PMID: 7330010 Document Number: 173509
The development of a new system for measuring the deformability of isolated erythrocyte membranes is described. This system, which uses ektacytometry of resealed erythrocyte membranes, enables one to directly measure membrane properties in the absence of internal viscosity effects. Preliminary observations have indicated that cross-linking membrane proteins gave rise to reduced membrane deformability.