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Incorporation of labeled 3H-leucine in the acidic protein of the brains of hibernating animals

Deriĭ, L.V.

Biulleten' Eksperimental'noi Biologii i Meditsiny 91(5): 546-548

1981

ISSN/ISBN: 0365-9615
PMID: 7260383
Document Number: 173273
3H-leucine was injected intraperitoneally to hibernating and awakening sousliks and to those being conscious for one or two weeks. Water-soluble brain protein extracts were separated by disc electrophoresis to determine relative radioactivity of the most acidic fraction which, under similar conditions, corresponds to the nerve-specific protein S-100. It was shown that in the brain cortex and reticular formation, the incorporation of the acidic protein drastically increases on awakening and reaches the maximum value on the 7th day. The high level of 3H-leucine incorporation into the hippocampus of the hibernating animals does not substantially change during the egress from hibernation. This may be related to the fact that during hibernation the hippocampus retains electrical activity.

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Emirbekov, E.Z.; Mukailov, M.I. 1971: Aspartate and alanine aminotransferase in the brain of hibernating and non-hibernating animals in hypotheramia Ukrains'kyi Biokhimichnyi Zhurnal 43(2): 202-203
Bhagavan, H.N.; Coursin, D.B. 1974: Nucleic acid and protein contents, and incorporation of L-[U-14C] leucine into proteins of brain and liver in biotin-deficient rats International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 44(3): 363-369
Koyama, T. 1972: Protein synthesis in the lens and its disturbance. 3. Influence of the basic condition on the accumulation of 14 C-L-leucine by rabbit lenses and the rate of reduction of 14 C-L-leucine incorporated into lens protein Nippon Ganka Gakkai Zasshi 76(8): 709-717
Hasselgren, P.O.; Almskog, B.; Lund, B.; von der Decken, A.; Nordström, G.; Seeman, T. 1982: Leucine incorporation into skeletal muscle proteins in vitro and protein synthesis by isolated ribosomes from skeletal muscle around a high velocity missile injury Acta Chirurgica Scandinavica. Supplementum 508: 337-344
Nefelova, M.V.; Pattakhov, A.A.; Silaev, A.B. 1971: Incorporation of C14-L-threonine and C14-L-leucine into the polymyxin M molecule Antibiotiki 16(6): 499-504
Rachev, R.R.; Ermenkov, K.I.; Charakchieva, S.B.; Dimitrov, M.I.; Filipova, E.H. 1977: Influence of thyroxine and ICl on the rate of in vivo incorporation of L-14C-leucine in subcellular structures Comptes Rendus de l'Academie Bulgare des Sciences: Sciences Mathematiques et Naturelles 30(11): 1633-1636
Sugano, H.; Sugano, I.; Jimbow, K.; Fitzpatrick, T.B. 1975: Tyrosinase-mediated inhibition of in vitro leucine incorporation into mouse melanoma by 4-isopropylcatechol Cancer Research 35(11 Part 1): 3126-3130
Chavko, M.; Kluchová, D.; Marsala, J. 1981: Incorporation of 14C-leucine into the proteins of spinal ganglia in vivo under conditions of partial ischaemia Physiologia Bohemoslovaca 30(3): 267-274
Roth, J.A.; Holmes, E.C.; Boddie, A.W.; Morton, D.L. 1975: Lymphocyte responses of lung cancer patients to tumor-associated antigen measured by leucine incorporation Journal of Thoracic and Cardiovascular Surgery 70(4): 613-618
Durliat, M. 1973: Study of the action of androgens on the incorporation of leucine in the male genital system of the white mouse Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 167(5): 629-634
Laval, J.; Frexinos, J.; Laval, H.P.; Serres, P.; Lenet, R.; Martinel, C.; Ribet, A. 1973: Isolated dog pancreas placed in extracorporeal circulation. Study on enzymatic secretion after injection of labeled leucine Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 167(1): 141-147
Kietzmann, M.; Lubach, D.; Müther, T. 1991: Incorporation of tritiated thymidine, leucine and histidine in murine tail epidermis after skin irritation (histoautoradiography) Deutsche Tierärztliche Wochenschrift 98(12): 453-456
Hopf, A.; Eckert, H. 1974: Distribution patterns of 14-C-psilocin in the brains of various animals Activitas Nervosa Superior 16(1): 64-66
Atherton, R.W.; Zimmerman, G.D. 1974: Comparisons between acetyl and butyrylcholinesterase activity in hibernating and non-hibernating ground squirrels, Spermophilus tridecemlineatus Environmental Physiology and Biochemistry 4(3): 97-103
Gheuens, J.; Karcher, D.; Noppe, M.; Lowenthal, A. 1979: Comparison of the brain specific protein alpha-albumin and GFA (glial fibrillary acidic protein) Acta Neurologica Belgica 79(4): 314-321
Matveev, V.F. 1970: Pathomorphologic changes in the brains of experimental animals with chronic lysergamide poisoning Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 70(12): 1856-1862
Huang, T.G.; Chen, L.; Huo, S.P. 1993: Correct use of the techniques of tritium labeled deoxythymidine incorporation into deoxyribonucleic acid Zhonghua Yi Xue Za Zhi 73(5): 308-309
Malínská, J.; Malínský, J.; Krajcí, D. 1974: Light, electron microscopical, and histochemical study of motor nerve cells in spinal cord of hibernating and non-hibernating hedgehog Activitas Nervosa Superior 16(2): 105
Savina, M.I.; Revich, G.G.; Mordukhovich, K.I. 1973: Incorporation of labeled precursors into nuclear proteins of normal and regenerating mouse liver Voprosy Meditsinskoi Khimii 19(6): 593-596
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