Experimental allergic encephalomyelitis in guinea pigs caused by meningococci

Kanchurin, A.K.; Koviazina, T.P.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 10: 48-52

1981


ISSN/ISBN: 0372-9311
PMID: 6800162
Document Number: 173211
The sensitization of guinea-pigs with the mixture of meningococci and heterologous-cerebral tissue commonly induces the development of the typical clinical and pathomorphological picture of allergic encephalomyelitis. Unlike Mycobacterium tuberculosis and other acid-resistant bacterial and much like Bordetella pertussis, meningococci are capable of inducing allergic encephalomyelitis when introduced in mixture with oil without cerebral tissue. The vaccinal strain induces allergic encephalomyelitis with a more moderate course of the disease.

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