The effects of physical training and nifedipine on patients recovering from acute myocardial infarction
Greco, V.; Trappolini, M.; Volpe, N.; De Rosa, L.; Latini, S.; Matteoli, S.
Giornale Italiano di Cardiologia 11(10): 1441-1444
1981
ISSN/ISBN: 0046-5968 PMID: 7341313 Document Number: 172851
10 patients recovering from acute myocardial infarction with stable symptomatology, underwent 3 subsequent ergometric trials: the first, basic, the second, after one month of practice on an ergometer bicycle and the third, with a longer period of training, after acute administration of nifedipine. The purpose of the study was to establish whether the administration of a drug such as nifedipine, acting principally on the after load, could further improve the working abilities of ischemic cardiopaths, already trained for muscular work. The results demonstrated that proper training can significantly increase the duration of muscular exercise, while the acute administration of 20 mg of nifedipine was not able to improve, to a greater degree, the working ability of patients who were already trained. The result was interpreted as being due to the inability of the trained organism to further increase the peripheral oxygen-saving mechanisms.