Treatment of Annular Elastolytic Giant Cell Granuloma with Topical Tretinoin
Wagenseller, A.; Larocca, C.; Vashi, N.A.
Journal of Drugs in Dermatology Jdd 16(7): 699-700
2017
ISSN/ISBN: 1545-9616 PMID: 28697223 Document Number: 17277
Annular elastolytic giant cell granuloma, also known as actinic granuloma, is a rare skin condition with a chronic course that is often resistant to treatment. Literature is sparse, and only a handful of case reports are available to guide treatment decisions. Typical first line treatment options include topical and intralesional steroids, topical pimecrolimus, and cryotherapy. Resistant cases have been treated with cyclosporine, systemic steroids, antimalarials, and oral retinoids. In particular, acitretin and isotretinoin have shown success in three cases. However, these medications can have side effects and require frequent lab monitoring. We present a case of a 47-year-old woman with bilateral forearm lesions consistent with annular elastolytic giant cell granuloma who was successfully treated with topical tretinoin.
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