The cytopathology of cerebrospinal fluid. II. Metastatic cancer, meningeal carcinomatosis and primary central nervous system neoplasms
Bigner, S.H.; Johnston, W.W.
Acta Cytologica 25(5): 461-479
1981
ISSN/ISBN: 0001-5547 PMID: 7025541 Document Number: 171691
The evaluation of CSF requires adaptation of basic cytopathologic principles to the specific neoplasms that involve the CNS. General criteria for detecting malignant cells in CSF are presented. The incidence and cytologic characteristics of specific metastatic tumors that involve CSF are reviewed and the incidence, pathogenesis and natural history of meningeal carcinomatosis discussed. The role of cytopathology in the detection and management of primary CNS tumors is presented. The cytologic characteristics of individual types of primary brain tumors and the application of fine needle aspiration biopsy to intracranial lesions are emphasized.