Systemic treatment of osteogenesis imperfecta
Albright, J.A.
Clinical Orthopaedics and Related Research 159: 88-96
1981
ISSN/ISBN: 0009-921X PMID: 7285474 Document Number: 170693
Seventy percent of published articles on the medical treatment of osteogenesis imperfecta have claimed beneficial results for 20 different agents. This observation conflicts with current practice since no form of treatment has been accepted as effective in dealing with the disease. A few medications or combinations of medications hold some promise, but adequate documentation must be availble before they can be accurately assessed. It is essential that the practitioner maintain a high degree of skepticism toward positive results of treatment regardless of the source. At the present time, no agent is available which will be of any value to the practitioner who has a patient with osteogenesis imperfecta.